Accurate characterization of the IVS7 repeat polymorphism of FVII gene and identification of three novel allelic forms.
نویسندگان
چکیده
Muriel Giansily-Blaizot1, Laurie Flory-Pigagniol1, Remi Favier2, Roula A. Farah3, Isabelle Martin-Toutain4, ElisabethVerdy5, Jean-Francois Schved1 1University Hospital Saint Eloi, Laboratory of Haematology, Montpellier, France; 2AP_HP Hospital Armand Trousseau, Laboratory of Haematology, Paris, France; 3Rizk Hospital, Department of Pediatrics, Beirut, Lebanon; 4AP_HP Pitie Salpetriere, Laboratory of Haematology, Paris, France; 5Hospital Tenon, Department of Haematology, Paris, France Letters to the Editor
منابع مشابه
Modulation of factor VII levels by intron 7 polymorphisms: population and in vitro studies.
Previous studies have established that factor VII gene (F7) polymorphisms (5'F7 and R353Q) contribute about one-third of factor VII (FVII) level variation in plasma. However, F7 genotyping in patients with cardiovascular disease has produced conflicting results. Population and expression studies were used to investigate the role of intron 7 (IVS7 ) polymorphisms, including repeat and sequence v...
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ورودعنوان ژورنال:
- Thrombosis and haemostasis
دوره 96 1 شماره
صفحات -
تاریخ انتشار 2006